Here are some quotes from Molyneux's LGC speech, found on www.gonintendo.com:

"(speaking over motion sensing controls) I realized, when I looked at myself in the mirror, I actually looked really stupid. Even with nothing in my hand, I get tired very, very quickly."

"I think motion-sensitivity is very, very useful, but I think the obvious way of doing it - unless you're dealing with a 15 to 20 minute experience at most of actually being hugely physical - is not where the opportunity lies here."

"(praising the DS) What I've found really fascinating is not using it to scribble with, but using it in a very clever, innovational way."

I completely see where Molyneux is coming from and I think he makes a valid point when he considers how people will appear when playing Wii games. Whether we find it shallow or not, most people are concerned with their appearance and don't like to do things that make them look silly--which is exactly what I expect the Wii to do.